To download a conference call about Moxxor
featuring Celeste Yarnall, PhD, and Jean Hofve, DVM, Moxxor Advisory
Board members, click below on the "Moxxor Talk" button. Please be
patient as this is a large MP3 file:
You know how important Omega-3 fatty acid
supplementation is for the health of yourself and your family, including
your four-legged family members. The anti-inflammatory effects of
Omega-3s EPA (eicosapentanoic acid) and DHA (docosahexanoic acid) have
been thoroughly researched, and are proven to be beneficial for people
as well as dogs and cats. But do you know how to choose the best Omega-3
supplement for your family? Let's look at the main sources:
The vast majority of plant-based oils are in
the form of Omega-6 fatty acids, which are already over-supplied in our
diets and our pets' diets. Flaxseeds and a few other seeds and nuts also
contain the Omega-3 alpha-linolenic acid (ALA). ALA has beneficial
effects of its own, particularly on skin and coat health, but dogs and
cats cannot convert more than 1-2% of it into EPA and DHA (the essential
fatty acids that are so important for our pets). The only bioavailable
forms of the most important Omega-3s must be obtained from an animal
source, such as marine lipids. Even many people cannot make the
conversion to EPA and DHA.
Fish and cod liver oil are the most common and
popular sources of EPA and DHA. However, these may be quite problematic.
Most salmon oil (and all salmon products from
the Atlantic Ocean, Scotland, and Norway) comes primarily from
farm-raised salmon,. These fish are grown in polluted, overcrowded pens,
they are heavily vaccinated, and fed antifungals, parasiticides, and
antibiotics, and they contain up to 10 times more mercury, dioxins,
PCBs, and other toxins than wild fish. Farmed salmon also pose a serious
threat to wild species in both Atlantic and Pacific oceans.
Additionally, about 1/3 of labeled “Alaska,” “wild,” and “wild-caught”
salmon are not truly wild, but bred and raised in hatcheries; their
release to the ocean appears to be threatening both wild salmon and
other fish such as herring.
Cod liver oil is commonly supplemented with Vitamins A and D, at levels
that could easily become toxic in dogs and cats. Moreover, a loophole in
the law allows non-cod species to be labeled as cod.
There are also oils made from other fish, such as menhaden (a threatened
keystone species, and the source of most unspecified “fish oil”).
Sardine, herring, and anchovy oils are—so far—more sustainable and
cleaner than most other fish oils.
Krill oil is a non-fish alternative Omega-3
product that is gaining in popularity. Krill (tiny red shrimp-like
crustaceans), are the major food source for many marine animals,
including fish, whales, seals, squid, and birds. Krill are utilized for
oil as well as being processed into food for farmed fish. The global
biomass of krill is enormous, but the problem is that they are being
harvested near critical feeding grounds of the animals that eat them,
potentially threatening dozens of species.
Greenlip Mussel Oil
Zealand greenlip mussels (Perna canaliculus, GLM) are grown under a
Sustainable Farming Program that ensures the long term viability of the
greenlip mussel industry, with minimum impact on the environment. GLM
are bi-valve mollusks known to be a rich source of 33 fatty acids, of
which 18 are Omega 3s (including EPA and DHA). One of GLM's unique array
of Omega 3s is ETA (eicosatetraenoic acid). ETA, which is not found in
any other foods to any measurable degree, has extremely powerful
GLM oil has the following fatty acid profile:
- (EPA) Eicosapentaenoic C20:5n-3: 4.7%
- (DHA) Docosahexaenoic c22:6n-3: 3%
- Palmitic C16:0: 14.2%
- Myristic C14:0: 0.9%
- Myristoleic C14:1: 0.1%
- Penadecanoic C15:0: 0.1%
- Hexadencenoic C16:1: 2.9%
- Magaric C17:0: 0.2%
- Heptadecenoic C17:1: 0.1%
- Stearic C18:0: 2.5%
- Oleic C18:1n-9: 52.8%
- Linoleic C18:2n-6: 12.1%
- Octadecadienic C18:2: 0.8%
- Alpha Linoleic C18:3n-3: 1.0%
- Arachidic C20:0: 0.2%
- Eicosenic C20:4n-9: 0.7%
- Eicosatetraenoic C20:4n-3: 0.1%
- Arachidonic C20:4n-6: 0.3%
- Heneicosapentaenoic C20:5n-3: 0.1%
- Docosanoic C22:0: 0.1%
- Docosapentaenoic C22:6n-3: 0.3%
- Tetracosanoic C24:0: 0.1%
Moxxor produces an ideal greenlip mussel oil: it is organic,
sustainably grown, cold-extracted, and certified to be free of mercury
and other toxins and pollutants. It also contains cold-pressed, organic
white grape seed husk extract and kiwifruit seed oil, which are loaded
with antioxidants that naturally deactivate free radicals; they also
serve as natural preservatives for the GLM oil.
In contrast to many marine oil products,
Moxxor is cold processed. As a result, it contains a higher level of
“polar” fatty acid molecules (which readily form bonds with surrounding
tissues) than other oils, making Moxxor more bioavailable. This, as well
as the absence of fillers or carrier oils, is what allows a very small
GLM oil capsule to contain more antioxidant power as the larger Krill
oil capsules and gigantic fish oil capsules.
But don't take our word for it! GLM oil has
been extensively studied in both humans and animals:
“GLME had a beneficial effect on the
clinical signs of dogs presumptively diagnosed with mild-to-moderate DJD.”
Pollard B, Guilford WG, Ankenbauer-Perkins KL. Clinical efficacy and
tolerance of an extract of green-lipped mussel (Perna canaliculus) in
dogs presumptively diagnosed with degenerative joint disease. N Z Vet
J. 2006 Jun;54(3):114-8.
“The change in total arthritis score by the end of 6 weeks showed there
was significant improvement (P <.05) in the test group versus the
control group. Significant improvements were also observed in joint pain
and swelling scores in the test group.” Bui LM, Bierer TL. Influence of
green lipped mussels (Perna canaliculus) in alleviating signs of
arthritis in dogs. Vet Ther. 2003 Winter;4(4):397-407.
“Most important, GLM has been shown to contain a unique omega-3 fatty
acid, eicosatetraenoic acid (ETA), which appears to act as dual
inhibitor of arachidonic acid oxygenation by both the cyclooxygenase
(COX) and lipoxygenase pathways. Arachidonic acid metabolites play a
major role in the inflammatory sequence. Unlike many nonsteroidal
anti-inflammatory drugs (NSAIDs), however, GLM is nongastrotoxic and
does not affect platelet aggregation, suggesting that ETA may
selectively block the pro-inflammatory COX-2 pathway rather than the
physiologically important COX-1 pathway.” Bierer TL, Bui LM. Improvement
of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus).
J Nutr. 2002 Jun;132(6 Suppl 2):1634S-6S.
“All four single [centered] studies reported positive clinical
improvement for GLM over a clinically relevant period of at least 2
months in mild to moderate OA.” Brien, S, et al. Systematic review of
the nutritional supplement Perna Canaliculus (green-lipped mussel) in
the treatment of osteoarthritis. QJM 2008 Mar;101(3):167-79.
In order to ensure freshness, the mussels grown for Moxxor are processed
in a facility built on the shores of the sound where they are grown and
harvested. In addition, the other two components of Moxxor, Sauvignon
Blanc grape seed husk extract and kiwifruit seed oil provide additional
antioxidant power, including all 8 members of the Vitamin E family.
These ingredients safeguard Moxxor's freshness and stability by
scavenging the oxygen free radicals that cause rancidity.